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Cellular and Molecular Networks in Chronic Myeloid Leukemia: The Leukemic Stem, Progenitor and Stromal Cell Interplay

The use of imatinib, second and third generation ABL tyrosine kinase inhibitors (TKI) (i.e. dasatinib, nilotinib, bosutinib and ponatinib) made CML a clinically manageable and, in a small percentage of cases, a cured disease. TKI therapy also turned CML blastic transformation into a rare event; howe...

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Detalhes bibliográficos
Publicado no:Curr Drug Targets
Main Authors: Perrotti, Danilo, Silvestri, Giovannino, Stramucci, Lorenzo, Yu, Justine, Trotta, Rossana
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970649/
https://ncbi.nlm.nih.gov/pubmed/27307150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389450117666160615074120
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