In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model

BACKGROUND: The protein cross-linking enzyme tissue transglutaminase (TG2; EC 2.3.2.13) is associated with the pathogenesis of various diseases, including cancer. Recently, the synthesis and initial evaluation of two high-potential radiolabelled irreversible TG2 inhibitors were reported by us. In th...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: van der Wildt, Berend, Wilhelmus, Micha M. M., Beaino, Wissam, Kooijman, Esther J. M., Schuit, Robert C., Bol, John G. J. M., Breve, John J. P., Pasternack, Ralf, Lammertsma, Adriaan A., Windhorst, Albert D., Drukarch, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970127/
https://ncbi.nlm.nih.gov/pubmed/29802556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-018-0388-2
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