Modulation of formin processivity by profilin and mechanical tension

Formins are major regulators of actin networks. They enhance actin filament dynamics by remaining processively bound to filament barbed ends. How biochemical and mechanical factors affect formin processivity are open questions. Monitoring individual actin filaments in a microfluidic flow, we report...

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Bibliographic Details
Published in:eLife
Main Authors: Cao, Luyan, Kerleau, Mikael, Suzuki, Emiko L., Wioland, Hugo, Jouet, Sandy, Guichard, Berengere, Lenz, Martin, Romet-Lemonne, Guillaume, Jegou, Antoine
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2018
Subjects:
Biochemistry and Chemical Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969902/
https://ncbi.nlm.nih.gov/pubmed/29799413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34176
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