A panel of correlates predicts vaccine-induced protection of rats against respiratory challenge with virulent Francisella tularensis

There are no defined correlates of protection for any intracellular pathogen, including the bacterium Francisella tularensis, which causes tularemia. Evaluating vaccine efficacy against sporadic diseases like tularemia using field trials is problematic, and therefore alternative strategies to test v...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: De Pascalis, Roberto, Hahn, Andrew, Brook, Helen M., Ryden, Patrik, Donart, Nathaniel, Mittereder, Lara, Frey, Blake, Wu, Terry H., Elkins, Karen L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969757/
https://ncbi.nlm.nih.gov/pubmed/29799870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198140
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