A panel of correlates predicts vaccine-induced protection of rats against respiratory challenge with virulent Francisella tularensis

There are no defined correlates of protection for any intracellular pathogen, including the bacterium Francisella tularensis, which causes tularemia. Evaluating vaccine efficacy against sporadic diseases like tularemia using field trials is problematic, and therefore alternative strategies to test v...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: De Pascalis, Roberto, Hahn, Andrew, Brook, Helen M., Ryden, Patrik, Donart, Nathaniel, Mittereder, Lara, Frey, Blake, Wu, Terry H., Elkins, Karen L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969757/
https://ncbi.nlm.nih.gov/pubmed/29799870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198140
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