Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal

To easily edit the genome of naïve human embryonic stem cells (hESC), we introduced a dual cassette encoding an inducible Cas9 into the AAVS1 site of naïve hESC (iCas9). The iCas9 line retained karyotypic stability, expression of pluripotency markers, differentiation potential, and stability in 5iLA...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Cycle
Asıl Yazarlar: Ferreccio, Amy, Mathieu, Julie, Detraux, Damien, Somasundaram, Logeshwaran, Cavanaugh, Christopher, Sopher, Bryce, Fischer, Karin, Bello, Thomas, M. Hussein, Abdiasis, Levy, Shiri, Cook, Savannah, Sidhu, Sonia B., Artoni, Filippo, Palpant, Nathan J., Reinecke, Hans, Wang, Yuliang, Paddison, Patrick, Murry, Charles, Jayadev, Suman, Ware, Carol, Ruohola-Baker, Hannele
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2018
Konular:
Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969550/
https://ncbi.nlm.nih.gov/pubmed/29466914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1442621
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller