Vascular Endothelial Growth Factor-A(165)b Restores Normal Glomerular Water Permeability in a Diphtheria-Toxin Mouse Model of Glomerular Injury

BACKGROUND/AIMS: Genetic cell ablation using the human diphtheria toxin receptor (hDTR) is a new strategy used for analysing cellular function. Diphtheria toxin (DT) is a cytotoxic protein that leaves mouse cells relatively unaffected, but upon binding to hDTR it ultimately leads to cell death. We u...

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Bibliografiske detaljer
Udgivet i:Nephron Clin Pract
Main Authors: Stevens, Megan, Neal, Christopher R., Salmon, Andrew H.J., Bates, David O., Harper, Steven J., Oltean, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2018
Fag:
Experimental Nephrology and Genetics: Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969078/
https://ncbi.nlm.nih.gov/pubmed/29393270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000485664
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