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Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats

PURPOSE: To investigate whether sheets of retina organoids derived from human embryonic stem cells (hESCs) can differentiate, integrate, and improve visual function in an immunodeficient rat model of severe retinal degeneration (RD). METHODS: 3D hESC-derived retina organoids were analyzed by quantit...

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Bibliografski detalji
Izdano u:Invest Ophthalmol Vis Sci
Glavni autori: McLelland, Bryce T., Lin, Bin, Mathur, Anuradha, Aramant, Robert B., Thomas, Biju B., Nistor, Gabriel, Keirstead, Hans S., Seiler, Magdalene J.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968836/
https://ncbi.nlm.nih.gov/pubmed/29847666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-23646
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