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Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats

PURPOSE: To investigate whether sheets of retina organoids derived from human embryonic stem cells (hESCs) can differentiate, integrate, and improve visual function in an immunodeficient rat model of severe retinal degeneration (RD). METHODS: 3D hESC-derived retina organoids were analyzed by quantit...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Invest Ophthalmol Vis Sci
Κύριοι συγγραφείς: McLelland, Bryce T., Lin, Bin, Mathur, Anuradha, Aramant, Robert B., Thomas, Biju B., Nistor, Gabriel, Keirstead, Hans S., Seiler, Magdalene J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Association for Research in Vision and Ophthalmology 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968836/
https://ncbi.nlm.nih.gov/pubmed/29847666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-23646
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