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Bone loss from Wnt inhibition mitigated by concurrent alendronate therapy

Dysregulated Wnt signaling is associated with the pathogenesis of cancers, fibrosis, and vascular diseases. Inhibition of Wnt signaling has shown efficacy in various pre-clinical models of these disorders. One of the key challenges in developing targeted anti-cancer drugs is to balance efficacy with...

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Detalhes bibliográficos
Publicado no:Bone Res
Main Authors: Madan, Babita, McDonald, Mitchell J., Foxa, Gabrielle E., Diegel, Cassandra R., Williams, Bart O., Virshup, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968037/
https://ncbi.nlm.nih.gov/pubmed/29844946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-018-0017-8
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