Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer

Hepatocellular carcinoma (HCC), accounting for 90% of primary liver cancer, is a lethal malignancy that is tightly associated with chronic hepatitis B virus (HBV) infection. HBV encodes a viral onco-protein, transactivator protein X (HBx), which interacts with proteins of hepatocytes to promote onco...

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Pubblicato in:Oncogenesis
Autori principali: Tse, Aki Pui-Wah, Sze, Karen Man-Fong, Shea, Queenie Tsung-Kwan, Chiu, Elley Yung-Tuen, Tsang, Felice Ho-Ching, Chiu, David Kung-Chun, Zhang, Misty Shuo, Lee, Derek, Xu, Iris Ming-Jing, Chan, Cerise Yuen-Ki, Koh, Hui-Yu, Wong, Chun-Ming, Zheng, Yong-Ping, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968027/
https://ncbi.nlm.nih.gov/pubmed/29799025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0052-8
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