Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway

Hypoxia is commonly found in cancers. Hypoxia, due to the lack of oxygen (O(2)) as the electron recipient, causes inefficient electron transfer through the electron transport chain at the mitochondria leading to accumulation of reactive oxygen species (ROS) which could create irreversible cellular d...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Kung-Chun Chiu, David, Pui-Wah Tse, Aki, Law, Cheuk-Ting, Ming-Jing Xu, Iris, Lee, Derek, Chen, Mengnuo, Kit-Ho Lai, Robin, Wai-Hin Yuen, Vincent, Wing-Sum Cheu, Jacinth, Wai-Hung Ho, Daniel, Wong, Chun-Ming, Zhang, Huafeng, Ng, Irene Oi-Lin, Chak-Lui Wong, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901483/
https://ncbi.nlm.nih.gov/pubmed/31819034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2155-3
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