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Tailoring the specificity of the type C feruloyl esterase FoFaeC from Fusarium oxysporum towards methyl sinapate by rational redesign based on small molecule docking simulations

The type C feruloyl esterase FoFaeC from Fusarium oxysporum is a newly discovered enzyme with high potential for use in the hydrolysis of lignocellulosic biomass but it shows low activity towards sinapates. In this work, small molecule docking simulations were employed in order to identify important...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Antonopoulou, Io, Hunt, Cameron, Cerullo, Gabriella, Varriale, Simona, Gerogianni, Alexandra, Faraco, Vincenza, Rova, Ulrika, Christakopoulos, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967792/
https://ncbi.nlm.nih.gov/pubmed/29795702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198127
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