Tailoring the specificity of the type C feruloyl esterase FoFaeC from Fusarium oxysporum towards methyl sinapate by rational redesign based on small molecule docking simulations

The type C feruloyl esterase FoFaeC from Fusarium oxysporum is a newly discovered enzyme with high potential for use in the hydrolysis of lignocellulosic biomass but it shows low activity towards sinapates. In this work, small molecule docking simulations were employed in order to identify important...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Antonopoulou, Io, Hunt, Cameron, Cerullo, Gabriella, Varriale, Simona, Gerogianni, Alexandra, Faraco, Vincenza, Rova, Ulrika, Christakopoulos, Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967792/
https://ncbi.nlm.nih.gov/pubmed/29795702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198127
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