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Tailoring the specificity of the type C feruloyl esterase FoFaeC from Fusarium oxysporum towards methyl sinapate by rational redesign based on small molecule docking simulations

The type C feruloyl esterase FoFaeC from Fusarium oxysporum is a newly discovered enzyme with high potential for use in the hydrolysis of lignocellulosic biomass but it shows low activity towards sinapates. In this work, small molecule docking simulations were employed in order to identify important...

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Vydáno v:PLoS One
Hlavní autoři: Antonopoulou, Io, Hunt, Cameron, Cerullo, Gabriella, Varriale, Simona, Gerogianni, Alexandra, Faraco, Vincenza, Rova, Ulrika, Christakopoulos, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967792/
https://ncbi.nlm.nih.gov/pubmed/29795702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198127
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