Estimation of the radiation-induced DNA double-strand breaks number by considering cell cycle and absorbed dose per cell nucleus

DNA double-strand breaks (DSBs) are thought to be the main cause of cell death after irradiation. In this study, we estimated the probability distribution of the number of DSBs per cell nucleus by considering the DNA amount in a cell nucleus (which depends on the cell cycle) and the statistical vari...

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Veröffentlicht in:J Radiat Res
Hauptverfasser: Mori, Ryosuke, Matsuya, Yusuke, Yoshii, Yuji, Date, Hiroyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Regular Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967466/
https://ncbi.nlm.nih.gov/pubmed/29800455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrx097
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