Investigation of dose-rate effects and cell-cycle distribution under protracted exposure to ionizing radiation for various dose-rates

During exposure to ionizing radiation, sub-lethal damage repair (SLDR) competes with DNA damage induction in cultured cells. By virtue of SLDR, cell survival increases with decrease of dose-rate, so-called dose-rate effects (DREs). Here, we focused on a wide dose-rate range and investigated the chan...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Matsuya, Yusuke, McMahon, Stephen J., Tsutsumi, Kaori, Sasaki, Kohei, Okuyama, Go, Yoshii, Yuji, Mori, Ryosuke, Oikawa, Joma, Prise, Kevin M., Date, Hiroyuki
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974424/
https://ncbi.nlm.nih.gov/pubmed/29844494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26556-5
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