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Estimation of the radiation-induced DNA double-strand breaks number by considering cell cycle and absorbed dose per cell nucleus

DNA double-strand breaks (DSBs) are thought to be the main cause of cell death after irradiation. In this study, we estimated the probability distribution of the number of DSBs per cell nucleus by considering the DNA amount in a cell nucleus (which depends on the cell cycle) and the statistical vari...

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Vydáno v:J Radiat Res
Hlavní autoři: Mori, Ryosuke, Matsuya, Yusuke, Yoshii, Yuji, Date, Hiroyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967466/
https://ncbi.nlm.nih.gov/pubmed/29800455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrx097
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