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OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos
Oxidative stress-induced DNA damage has been well acknowledged as a major cause leading to cell death, which is etiologically linked to ischemic injury and degenerative alterations. The most common oxidation product of DNA is base lesion 8-oxo-7,8-dihydroguanine (8-oxoG), which is repaired by 8-oxoG...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5967321/ https://ncbi.nlm.nih.gov/pubmed/29795387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0680-0 |
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