BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51

DNA double-strand breaks (DSBs) are a type of lethal DNA damage. The repair of DSBs requires tight coordination between the factors modulating chromatin structure and the DNA repair machinery. BRG1, the ATPase subunit of the chromatin remodelling complex Switch/Sucrose non-fermentable (SWI/SNF), is...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Qi, Wenjing, Wang, Ruoxi, Chen, Hongyu, Wang, Xiaolin, Xiao, Ting, Boldogh, Istvan, Ba, Xueqing, Han, Liping, Zeng, Xianlu
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294775/
https://ncbi.nlm.nih.gov/pubmed/25395584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.159103
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