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BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51
DNA double-strand breaks (DSBs) are a type of lethal DNA damage. The repair of DSBs requires tight coordination between the factors modulating chromatin structure and the DNA repair machinery. BRG1, the ATPase subunit of the chromatin remodelling complex Switch/Sucrose non-fermentable (SWI/SNF), is...
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| Publicado en: | J Cell Sci |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Company of Biologists
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294775/ https://ncbi.nlm.nih.gov/pubmed/25395584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.159103 |
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