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BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51

DNA double-strand breaks (DSBs) are a type of lethal DNA damage. The repair of DSBs requires tight coordination between the factors modulating chromatin structure and the DNA repair machinery. BRG1, the ATPase subunit of the chromatin remodelling complex Switch/Sucrose non-fermentable (SWI/SNF), is...

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Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Qi, Wenjing, Wang, Ruoxi, Chen, Hongyu, Wang, Xiaolin, Xiao, Ting, Boldogh, Istvan, Ba, Xueqing, Han, Liping, Zeng, Xianlu
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294775/
https://ncbi.nlm.nih.gov/pubmed/25395584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.159103
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