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Identification of small molecule inhibitors of the Chikungunya virus nsP1 RNA capping enzyme
Chikungunya virus (CHIKV) is an arthropod-borne alphavirus. Alphaviruses are positive strand RNA viruses that require a 5´ cap structure to direct translation of the viral polyprotein and prevent degradation of the viral RNA genome by host cell nucleases. Formation of the 5´ RNA cap is orchestrated...
में बचाया:
| में प्रकाशित: | Antiviral Res |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5966835/ https://ncbi.nlm.nih.gov/pubmed/29680670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.03.013 |
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