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Digenic variants of planar cell polarity genes in human neural tube defect patients

Neural tube defects (NTDs) are considered to be a complex genetic disorder, although the identity of the genetic factors remains largely unknown. Mouse model studies suggest a multifactorial oligogenic pattern of inheritance for NTDs, yet evidence from published human studies is surprisingly absent....

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Bibliographic Details
Published in:Mol Genet Metab
Main Authors: Wang, Linlin, Xiao, Yanhui, Tian, Tian, Jin, Lei, Lei, Yunping, Finnell, Richard H., Ren, Aiguo
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966321/
https://ncbi.nlm.nih.gov/pubmed/29573971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2018.03.005
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