Hypomethylation of GRHL3 gene is associated with the occurrence of neural tube defects

AIM: To investigate the relationship between GRHL3 methylation and the etiology of neural tube defects (NTDs). MATERIALS & METHODS: Analyze data from a genome-wide DNA methylation array. Targeted DNA methylation analysis was performed for 46 cases and 23 controls. At last, grhl3 overexpression a...

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Vydáno v:Epigenomics
Hlavní autoři: Tian, Tian, Wang, Linlin, Shen, Yan, Zhang, Bo, Finnell, Richard H, Ren, Aiguo
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Medicine Ltd 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077761/
https://ncbi.nlm.nih.gov/pubmed/29587534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2018-0016
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