Somatic and de novo Germline Variants of MEDs in Human Neural Tube Defects

BACKGROUND: Neural tube defects (NTDs) are among the most common and severe congenital defects in humans. Their genetic etiology is complex and remains poorly understood. The Mediator complex (MED) plays a vital role in neural tube development in animal models. However, no studies have yet examined...

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Bibliografiska uppgifter
I publikationen:Front Cell Dev Biol
Huvudupphovsmän: Tian, Tian, Cao, Xuanye, Chen, Yongyan, Jin, Lei, Li, Zhiwen, Han, Xiao, Lin, Ying, Wlodarczyk, Bogdan J., Finnell, Richard H., Yuan, Zhengwei, Wang, Linlin, Ren, Aiguo, Lei, Yunping
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Cell and Developmental Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969791/
https://ncbi.nlm.nih.gov/pubmed/33748132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.641831
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