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A feasibility study of colorectal cancer diagnosis via circulating tumor DNA derived CNV detection

Circulating tumor DNA (ctDNA) has shown great promise as a biomarker for early detection of cancer. However, due to the low abundance of ctDNA, especially at early stages, it is hard to detect at high accuracies while keeping sequencing costs low. Here we present a pilot stage study to detect large...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Molparia, Bhuvan, Oliveira, Glenn, Wagner, Jennifer L., Spencer, Emily G., Torkamani, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965833/
https://ncbi.nlm.nih.gov/pubmed/29791457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196826
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