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Mapping interactions between p27 and RhoA that stimulate cell migration
p27 mediates cell cycle arrest by binding to and inhibiting cyclin-dependent kinase (Cdk)/cyclin complexes, but p27 can also contribute to pro-oncogenic signaling upon mislocalization to the cytoplasm. Cytoplasmic p27 stimulates cell migration by associating with RhoA and interfering with the exchan...
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| Опубликовано в: : | J Mol Biol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5965279/ https://ncbi.nlm.nih.gov/pubmed/29410088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.01.017 |
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