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Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

We performed integrated genomic, transcriptomic and proteomic profiling of 150 pancreatic ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low neoplastic cellularity. Deep whole-exome sequencing revealed recurrent somatic mutations in KRAS, TP53, CDKN2A, SMAD4, RNF43, AR...

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Bibliografski detalji
Izdano u:Cancer Cell
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964983/
https://ncbi.nlm.nih.gov/pubmed/28810144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.07.007
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