Clinical study of genomic drivers in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDA) is a lethal cancer with complex genomes and dense fibrotic stroma. This study was designed to identify clinically relevant somatic aberrations in pancreatic cancer genomes of patients with primary and metastatic disease enrolled and treated in two c...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Barrett, Michael T, Deiotte, Ray, Lenkiewicz, Elizabeth, Malasi, Smriti, Holley, Tara, Evers, Lisa, Posner, Richard G, Jones, Timothy, Han, Haiyong, Sausen, Mark, Velculescu, Victor E, Drebin, Jeffrey, O'Dwyer, Peter, Jameson, Gayle, Ramanathan, Ramesh K, Von Hoff, Daniel D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Genetics & Genomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558689/
https://ncbi.nlm.nih.gov/pubmed/28720843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.209
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