Clonal Evolution and Therapeutic Resistance in Solid Tumors

Tumors frequently arise as a result of an acquired genomic instability and the subsequent evolution of neoplastic populations with variable genomes. A barrier to the study of the somatic genetics of human solid tumors in vivo is the presence of admixtures of non-neoplastic cells with normal genomes...

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Bibliografske podrobnosti
Main Authors: Barrett, Michael T., Lenkiewicz, Elizabeth, Evers, Lisa, Holley, Tara, Ruiz, Christian, Bubendorf, Lukas, Sekulic, Aleksander, Ramanathan, Ramesh K., Von Hoff, Daniel D.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556559/
https://ncbi.nlm.nih.gov/pubmed/23372550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00002
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