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Clonal evolution in hematologic malignancies and therapeutic implications
The ability of cancer to evolve and adapt is a principal challenge to therapy in general, and to the paradigm of targeted therapy in particular. This ability is fueled by the co-existence of multiple, genetically heterogeneous subpopulations within the cancer cell population. Increasing evidence has...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3934006/ https://ncbi.nlm.nih.gov/pubmed/23979521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.248 |
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