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Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies

Clonal hematopoiesis (CH) broadly describes the expansion of a clonal population of blood cells with one or more somatic mutations. Individuals with CH are at greater risk for hematological malignancies, cardiovascular disease, and increased mortality from non-hematological cancers. Understanding th...

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Bibliografiske detaljer
Udgivet i:Cell Stem Cell
Main Authors: Bowman, Robert L., Busque, Lambert, Levine, Ross L.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804896/
https://ncbi.nlm.nih.gov/pubmed/29395053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.01.011
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