Advancing a clinically relevant perspective of the clonal nature of cancer

Cancers frequently arise as a result of an acquired genomic instability and the subsequent clonal evolution of neoplastic cells with variable patterns of genetic aberrations. Thus, the presence and behaviors of distinct clonal populations in each patient's tumor may underlie multiple clinical p...

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Detalhes bibliográficos
Main Authors: Ruiz, Christian, Lenkiewicz, Elizabeth, Evers, Lisa, Holley, Tara, Robeson, Alex, Kiefer, Jeffrey, Demeure, Michael J., Hollingsworth, Michael A., Shen, Michael, Prunkard, Donna, Rabinovitch, Peter S., Zellweger, Tobias, Mousses, Spyro, Trent, Jeffrey M., Carpten, John D., Bubendorf, Lukas, Von Hoff, Daniel, Barrett, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141975/
https://ncbi.nlm.nih.gov/pubmed/21730190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104009108
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