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Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma
We performed integrated genomic, transcriptomic and proteomic profiling of 150 pancreatic ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low neoplastic cellularity. Deep whole-exome sequencing revealed recurrent somatic mutations in KRAS, TP53, CDKN2A, SMAD4, RNF43, AR...
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| 發表在: | Cancer Cell |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5964983/ https://ncbi.nlm.nih.gov/pubmed/28810144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.07.007 |
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