QSAR analysis of substituent effects on tambjamine anion transporters

The transmembrane anion transport activity of 43 synthetic molecules based on the structure of marine alkaloid tambjamine were assessed in model phospholipid (POPC) liposomes. The anionophoric activity of these molecules showed a parabolic dependence with lipophilicity, with an optimum range for tra...

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Detaylı Bibliyografya
Yayımlandı:Chem Sci
Asıl Yazarlar: Knight, Nicola J., Hernando, Elsa, Haynes, Cally J. E., Busschaert, Nathalie, Clarke, Harriet J., Takimoto, Koji, García-Valverde, María, Frey, Jeremy G., Quesada, Roberto, Gale, Philip A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2016
Konular:
Chemistry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964965/
https://ncbi.nlm.nih.gov/pubmed/29899901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03932k
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