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QSAR analysis of substituent effects on tambjamine anion transporters

The transmembrane anion transport activity of 43 synthetic molecules based on the structure of marine alkaloid tambjamine were assessed in model phospholipid (POPC) liposomes. The anionophoric activity of these molecules showed a parabolic dependence with lipophilicity, with an optimum range for tra...

詳細記述

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書誌詳細
出版年:Chem Sci
主要な著者: Knight, Nicola J., Hernando, Elsa, Haynes, Cally J. E., Busschaert, Nathalie, Clarke, Harriet J., Takimoto, Koji, García-Valverde, María, Frey, Jeremy G., Quesada, Roberto, Gale, Philip A.
フォーマット: Artigo
言語:Inglês
出版事項: Royal Society of Chemistry 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964965/
https://ncbi.nlm.nih.gov/pubmed/29899901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03932k
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