Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres

Background: Although thousands of clinical isolates of Plasmodium falciparum are being sequenced and analysed by short read technology, the data do not resolve the highly variable subtelomeric regions of the genomes that contain polymorphic gene families involved in immune evasion and pathogenesis....

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Foilsithe in:Wellcome Open Res
Main Authors: Otto, Thomas D., Böhme, Ulrike, Sanders, Mandy, Reid, Adam, Bruske, Ellen I., Duffy, Craig W., Bull, Pete C., Pearson, Richard D., Abdi, Abdirahman, Dimonte, Sandra, Stewart, Lindsay B., Campino, Susana, Kekre, Mihir, Hamilton, William L., Claessens, Antoine, Volkman, Sarah K., Ndiaye, Daouda, Amambua-Ngwa, Alfred, Diakite, Mahamadou, Fairhurst, Rick M., Conway, David J., Franck, Matthias, Newbold, Chris I., Berriman, Matt
Formáid: Artigo
Teanga:Inglês
Foilsithe: F1000 Research Limited 2018
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964635/
https://ncbi.nlm.nih.gov/pubmed/29862326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.14571.1
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