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Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis

Sphingolipids (SLs) are an integral part of all eukaryotic cellular membranes. In addition, they have indispensable functions as signalling molecules controlling a myriad of cellular events. Disruption of either the de novo synthesis or the degradation pathways has been shown to have detrimental eff...

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Detalhes bibliográficos
Publicado no:Parasitology
Main Authors: MINA, JOHN G. M., DENNY, P. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964470/
https://ncbi.nlm.nih.gov/pubmed/28637533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0031182017001081
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