THE PROTOZOAN INOSITOL PHOSPHORYLCERAMIDE SYNTHASE: A NOVEL DRUG TARGET WHICH DEFINES A NEW CLASS OF SPHINGOLIPID SYNTHASE

Sphingolipids are ubiquitous and essential components of eukaryotic membranes, particularly the plasma membrane. The biosynthetic pathway for the formation of these lipid species is conserved up to the formation of sphinganine. However, a divergence is apparent in the synthesis of complex sphingolip...

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Hlavní autoři: Denny, Paul W., Shams-Eldin, Hosam, Price, Helen. P., Smith, Deborah F., Schwarz, Ralph T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817671/
https://ncbi.nlm.nih.gov/pubmed/16861742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M600796200
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