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Drug repurposing: mining protozoan proteomes for targets of known bioactive compounds

OBJECTIVE: To identify potential opportunities for drug repurposing by developing an automated approach to pre-screen the predicted proteomes of any organism against databases of known drug targets using only freely available resources. MATERIALS AND METHODS: We employed a combination of Ruby script...

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Detalhes bibliográficos
Main Authors: Sateriale, Adam, Bessoff, Kovi, Sarkar, Indra Neil, Huston, Christopher D
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932453/
https://ncbi.nlm.nih.gov/pubmed/23757409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2013-001700
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