Energy balance modulation impacts epigenetic reprogramming, ERα and ERβ expression, and mammary tumor development in MMTV-neu transgenic mice

The association between obesity and breast cancer risk and prognosis is well established in ER-positive disease but less clear in HER2-positive disease. Here, we report preclinical evidence suggesting weight maintenance through calorie restriction may limit risk of HER2-positive breast cancer. In fe...

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Vydáno v:Cancer Res
Hlavní autoři: Rossi, Emily L., Dunlap, Sarah M., Bowers, Laura W., Khatib, Subreen A., Doerstling, Steven S., Smith, Laura A., Ford, Nikki A., Holley, Darcy, Brown, Powel H., Estecio, Marcos R., Kusewitt, Donna F., deGraffenried, Linda A., Bultman, Scott J., Hursting, Stephen D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964334/
https://ncbi.nlm.nih.gov/pubmed/28373182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2795
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