Energy balance modulation impacts epigenetic reprogramming, ERα and ERβ expression, and mammary tumor development in MMTV-neu transgenic mice

The association between obesity and breast cancer risk and prognosis is well established in ER-positive disease but less clear in HER2-positive disease. Here, we report preclinical evidence suggesting weight maintenance through calorie restriction may limit risk of HER2-positive breast cancer. In fe...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Rossi, Emily L., Dunlap, Sarah M., Bowers, Laura W., Khatib, Subreen A., Doerstling, Steven S., Smith, Laura A., Ford, Nikki A., Holley, Darcy, Brown, Powel H., Estecio, Marcos R., Kusewitt, Donna F., deGraffenried, Linda A., Bultman, Scott J., Hursting, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964334/
https://ncbi.nlm.nih.gov/pubmed/28373182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2795
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