Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

Microglia are highly motile glial cells that are proposed to mediate synaptic pruning during neuronal circuit formation. Disruption of signaling between microglia and neurons leads to an excess of immature synaptic connections, thought to be the result of impaired phagocytosis of synapses by microgl...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Weinhard, Laetitia, di Bartolomei, Giulia, Bolasco, Giulia, Machado, Pedro, Schieber, Nicole L., Neniskyte, Urte, Exiga, Melanie, Vadisiute, Auguste, Raggioli, Angelo, Schertel, Andreas, Schwab, Yannick, Gross, Cornelius T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964317/
https://ncbi.nlm.nih.gov/pubmed/29581545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03566-5
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