Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

Microglia are highly motile glial cells that are proposed to mediate synaptic pruning during neuronal circuit formation. Disruption of signaling between microglia and neurons leads to an excess of immature synaptic connections, thought to be the result of impaired phagocytosis of synapses by microgl...

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Foilsithe in:Nat Commun
Main Authors: Weinhard, Laetitia, di Bartolomei, Giulia, Bolasco, Giulia, Machado, Pedro, Schieber, Nicole L., Neniskyte, Urte, Exiga, Melanie, Vadisiute, Auguste, Raggioli, Angelo, Schertel, Andreas, Schwab, Yannick, Gross, Cornelius T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964317/
https://ncbi.nlm.nih.gov/pubmed/29581545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03566-5
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