Heterozygous diploid and interspecies SCRaMbLEing

SCRaMbLE (Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution) is a genome restructuring technique that can be used in synthetic genomes such as that of Sc2.0, the synthetic yeast genome, which contains hundreds to thousands of strategically positioned loxPsym sites. SCRaM...

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Udgivet i:Nat Commun
Main Authors: Shen, Michael J., Wu, Yi, Yang, Kun, Li, Yunxiang, Xu, Hui, Zhang, Haoran, Li, Bing-Zhi, Li, Xia, Xiao, Wen-Hai, Zhou, Xiao, Mitchell, Leslie A., Bader, Joel S., Yuan, Yingjin, Boeke, Jef D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964232/
https://ncbi.nlm.nih.gov/pubmed/29789590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04157-0
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