Precise control of SCRaMbLE in synthetic haploid and diploid yeast

Compatibility between host cells and heterologous pathways is a challenge for constructing organisms with high productivity or gain of function. Designer yeast cells incorporating the Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) system provide a platform...

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Vydáno v:Nat Commun
Hlavní autoři: Jia, Bin, Wu, Yi, Li, Bing-Zhi, Mitchell, Leslie A., Liu, Hong, Pan, Shuo, Wang, Juan, Zhang, Hao-Ran, Jia, Nan, Li, Bo, Shen, Michael, Xie, Ze-Xiong, Liu, Duo, Cao, Ying-Xiu, Li, Xia, Zhou, Xiao, Qi, Hao, Boeke, Jef D., Yuan, Ying-Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964104/
https://ncbi.nlm.nih.gov/pubmed/29789567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03084-4
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