Parathyroid Hormone-Related Protein Negatively Regulates Tumor Cell Dormancy Genes in a PTHR1/Cyclic AMP-Independent Manner

Parathyroid hormone-related protein (PTHrP) expression in breast cancer is enriched in bone metastases compared to primary tumors. Human MCF7 breast cancer cells “home” to the bones of immune deficient mice following intracardiac inoculation, but do not grow well and stain negatively for Ki67, thus...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Johnson, Rachelle W., Sun, Yao, Ho, Patricia W. M., Chan, Audrey S. M., Johnson, Jasmine A., Pavlos, Nathan J., Sims, Natalie A., Martin, T. John
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964132/
https://ncbi.nlm.nih.gov/pubmed/29867773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00241
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