Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis

Understanding the molecular signaling in programmed cell death is vital to a practical understanding of inflammation and immune cell function. Here we identify a previously unrecognized mechanism that functions to downregulate the necrosome, a central signaling complex involved in inflammation and n...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Alturki, Norah A., McComb, Scott, Ariana, Ardeshir, Rijal, Dikchha, Korneluk, Robert G., Sun, Shao-Cong, Alnemri, Emad, Sad, Subash
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964080/
https://ncbi.nlm.nih.gov/pubmed/29789521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0672-0
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge