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Imprinted gene dysregulation in a Tet1 null mouse model is stochastic and variable in the germline and offspring
Imprinted genes are expressed from one parental allele and regulated by differential DNA methylation at imprinting control regions (ICRs). ICRs are reprogrammed in the germline through erasure and re-establishment of DNA methylation. Although much is known about DNA methylation establishment, DNA de...
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| 出版年: | Development |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Ltd
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963867/ https://ncbi.nlm.nih.gov/pubmed/29530881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.160622 |
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