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Imprinted gene dysregulation in a Tet1 null mouse model is stochastic and variable in the germline and offspring
Imprinted genes are expressed from one parental allele and regulated by differential DNA methylation at imprinting control regions (ICRs). ICRs are reprogrammed in the germline through erasure and re-establishment of DNA methylation. Although much is known about DNA methylation establishment, DNA de...
Guardat en:
| Publicat a: | Development |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Company of Biologists Ltd
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963867/ https://ncbi.nlm.nih.gov/pubmed/29530881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.160622 |
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